Conjugated Oral versus Transdermal Estrogen Replacement in Girls with Turner Syndrome: A Pilot Comparative Study
نویسندگان
چکیده
منابع مشابه
Late-Onset Puberty Induction by Transdermal Estrogen in Turner Syndrome Girls—A Longitudinal Study
Objective Estrogen replacement therapy (ERT) for Turner syndrome (TS) is a widely discussed topic; however, the optimal model of ERT for patients with delayed diagnosis and/or initiation of therapy is still unclear, mainly due to insufficient data. We present the results of a prospective observational single-center study in which the efficacy of late-onset puberty induction by one-regimen trans...
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Systemic hypertension, ischemic heart disease, and stroke are the major factors that reduce lifespan in Turner syndrome. Importantly, high blood pressure (BP) is the most readily treatable risk factor for aortic dissection and rupture that occurs in young women with Turner syndrome. A review of 65 cases of aortic dissection in girls and women with Turner syndrome identified concomitant congenit...
متن کاملOptimizing estrogen replacement treatment in Turner syndrome.
Estrogen has a biphasic effect on growth, stimulatory at low doses but inhibitory at higher doses. Therefore, designing optimal sex hormone replacement treatment in girls with Turner syndrome (TS) who are being treated with growth hormone (GH) involves considering the dose and form of the estrogen as well as the route and timing of its administration. We report here a preliminary analysis of a ...
متن کاملCare of girls and women with Turner syndrome: a guideline of the Turner Syndrome Study Group.
OBJECTIVES The objective of this work is to provide updated guidelines for the evaluation and treatment of girls and women with Turner syndrome (TS). PARTICIPANTS The Turner Syndrome Consensus Study Group is a multidisciplinary panel of experts with relevant clinical and research experience with TS that met in Bethesda, Maryland, April 2006. The meeting was supported by the National Institute...
متن کاملCortical brain morphology in young, estrogen-naive, and adolescent, estrogen-treated girls with Turner syndrome.
Turner syndrome (TS) is a genetic condition that permits direct investigation of the complex interaction among genes, hormones, behavior, and brain development. Here, we used automated segmentation and surface-based morphometry to characterize the differences in brain morphology in children (n = 30) and adolescents (n = 16) with TS relative to age- and sex-matched control groups (n = 21 and 24,...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2009
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2008-2123